Early Detection of Acute Kidney Injury With Neutrophil Gelatinase-Associated Lipocalin
نویسندگان
چکیده
منابع مشابه
Early detection of acute kidney injury with neutrophil gelatinase-associated lipocalin.
Acute kidney injury (AKI) after cardiac procedures and in critically ill patients has been consistently associated with increased cost of care, complications, permanent kidney dysfunction, and higher mortality (1,2). There is an immeiate and present need to detect acute AKI before the rise in erum creatinine (Cr) and the development of oliguria, ecause by that time patients are often resistant ...
متن کاملNeutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL) is an early marker of acute kidney injury (AKI). METHODS AND RESULTS Urine NGAL and serum NGAL (sNGAL) were assessed at 2, 6, 24, and 48 hours after contrast media (CM) exposure in 458 high-risk patients (development set). Optimal thresholds in predicting contrast-induced AKI (serum creatinine [sCr] increase ≥0.3 mg/dL at 48 hours a...
متن کاملUrinary neutrophil gelatinase-associated lipocalin is an early predictor of acute kidney injury in premature infants
Urinary neutrophil gelatinase-associated lipocalin (uNGAL) is produced in response to tubular epithelial injury and is a biomarker of tubulointerstitial injury. The aim of the present study was to examine whether acute kidney injury (AKI) could be predicted by measuring uNGAL in very low-birth weight (VLBW) infants. Forty VLBW infants with birthweight below 1,500 g were enrolled in the present ...
متن کاملValue of Plasma/Serum Neutrophil Gelatinase-Associated Lipocalin in Detection of Pediatric Acute Kidney Injury; a Systematic Review and Meta-Analysis
Background: Major attention has been drawn to the prognostic value of plasma/serum neutrophil gelatinase-associated lipocalin (NGAL) in detection of acute kidney injury (AKI) in children, but still no consensus has been reached. Accordingly, the present study aimed to assess the diagnostic value of this biomarker in detection of acute kidney injury in children through a systematic review and me...
متن کاملDiagnostic Value of Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Detection of Pediatric Acute Kidney Injury; a Systematic Review and Meta-Analysis
Background: Two questions about diagnostic value of urinary neutrophil gelatin associated lipocalin (uNGAL) in detection of acute kidney injury (AKI) in children have remained unanswered; first, which cut-off point of uNGAL has the highest value in detection of AKI; and second when is the best time for measuring this biomarker in a patient? Accordingly, the present study aimed to conduct a syst...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2011
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2010.11.050